Deeper Insights for Every Lab

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Our Next-Generation High-Content Screening Platform 

Why Choose the ImageXpress HCS.ai System


Empower your team to obtain high-definition images and robust data from a wide range of assays with the ImageXpress HCS.ai System, the next-generation solution that evolves with your research needs. 

The new ImageXpress HCS.ai High-Content Screening System goes beyond data capture, delivering high-speed acquisition, AI-powered analysis, and advanced imaging to turn complex data into discoveries.

Built for 2D and 3D assays, it offers high-definition imaging, deep-learning segmentation, and a modular, upgradeable design that evolves with your research. More than an imaging system, ImageXpress HCS.ai accelerates workflows, enhances reproducibility, and unlocks deeper insights to drive scientific progress.

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Up and Running – Fast

Start screening in minutes with the intuitive MetaXpress® Acquire software, eliminating complex setup and accelerating your research.

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Twice the Speed**

Boost your acquisition speed and accelerate your discovery with a redesigned optical system that delivers unprecedented performance.

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Superior Data Quality

Unlock deeper insights with 2x better signal-to- background** and powerful, AI-enabled IN Carta® software.

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Affordable Innovation

Experience top-tier performance while future-proofing your investment with unmatched upgrade flexibility and cost-effective modular design.

Tour the ImageXpress HCS.ai High-Content Screening System

Join senior field application scientist, Serena Cervantes for a detailed walk-through of the ImageXpress HCS.ai system, featuring the latest MetaXpress Acquire Software and the advanced AI-powered IN Carta Image Analysis Software.

Put our system to the test 

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Experience it first

See the ImageXpress HCS.ai system in action with a free demo and consultation.

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Industry-leading expertise

Access expert application scientists who will help tailor a workflow to your specific needs.

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Streamlined purchasing

Get a customized business plan and support for your investment.

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Global support

Partner with a trusted leader for local and global support wherever you are.

Request a demo

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AI-powered cell imaging is here — no coding, just discovery

IN Carta Image Analysis Software

Provides robust, quantitative results from complex biological images and datasetsAchieve flawless cell segmentationTrain custom AI models in a single clickClassify subtle phenotypic changes with hundreds of featuresAnalyze the most challenging 2D, 3D, and 4D datasets

MetaXpress Acquire High-Content Image Acquisition Software

Intuitive image acquisition software for a wide range of applications MetaXpress Acquire High-Content Image Acquisition Software is a comprehensive solution for high-content imaging, designed for use with our ImageXpress HCS.ai High-Content Screening System. An intuitive interface and guided workflows streamline even complex imaging assays, enabling you to start generating data in minutes. Seamless integration with our AI-powered IN Carta Image Analysis software empowers you to unlock new discoveries through the power of machine learning.

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Put our system to the test

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Experience it first

See the ImageXpress HCS.ai system in action with a free demo and consultation.

expertise-white-en

Industry-leading expertise

Access expert application scientists who will help tailor a workflow to your specific needs.

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Streamlined purchasing

Get a customized business plan and support for your investment.

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Global support

Partner with a trusted leader for local and global support wherever you are.

Request a demo

Molecular Devices: A life science company

270,000+

CITATIONS ACROSS OUR
PORTFOLIO

160,000+

SOLUTIONS IN LABS
WORLDWIDE

40

HARDWARE & SOFTWARE
TECHNOLOGY PLATFORM

A trusted life science partner to researchers worldwide

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**Compared to the previous generation ImageXpress platform. The data is available on request.