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Get it Right the First Time. Accelerated Cloning for Therapeutic Discovery.

Every breakthrough you make has the power to change a life. By transforming science into therapies, you’re redefining what’s possible for patients around the world. With tools that allow you to fast-track your research, minimize rework, and reduce the likelihood of errors, you can focus on what truly matters – delivering life-changing therapies.

The ClonePix® 2 Enhanced for Monoclonality Verification combines high-throughput fluorescent imaging with antibody-based detection to screen, rank, and pick only the most productive and monoclonal clones. By reducing labor-intensive steps and boosting confidence in early decisions, you gain time to focus on innovation, not validation.

At every step, your dedication ensures therapies are precise, reliable, and safe. Together, your work is transforming science – and lives.

Why It Matters

In the race to develop safe, effective therapies, early clone selection is one of the most critical steps — and one of the most overlooked. Whether you're developing monoclonal antibodies, cell-based therapies, or recombinant proteins, every mistake at this stage can introduce delays, regulatory risk, or product inconsistencies down the line.

The ClonePix 2 Enhanced for Monoclonality Verification helps researchers accelerate discovery and avoid costly rework with high-resolution imaging, fluorescent screening, and productivity ranking — all in a single automated platform. The result? Verified clones. Faster timelines. More confident decisions.

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ClonePix 2 Enhanced for Monoclonality Verification

The enhanced ClonePix 2 system offers high-resolution single-cell imaging for rapid monoclonal verification on day zero, reducing screening rounds and enabling quicker selection of high producers. Picking and analysis, enhancing efficiency and precision in the lab.


Learn More About Tomorrow's Innovations, Today

Built for Biopharma Workflows
  • Monoclonality assurance to meet IND and regulatory requirements
  • Antibody secretion detection using fluorescent and label-free assays
  • Colony ranking based on morphology and productivity
  • Real-time image documentation and audit trails
  • High-throughput performance with minimal manual input

ClonePix 2 Enhanced for Monoclonality Verification streamlines the earliest, most error-prone step of therapeutic development, helping researchers move from transfection to therapeutic-grade clone with speed and certainty.

From Frustration to Confidence: How ClonePix Solves Your Biggest Pain Points

Even the most promising therapeutic programs can stall due to inefficiencies in early-stage clone screening. Manual workflows leave too much to chance and too many hours on the table. Here’s how the ClonePix 2 Enhanced for Monoclonality Verification helps overcome common obstacles in cell line development:

Too Many Clones, Not Enough Time

Pain Point: Manual screening slows progress and increases the risk of missing high performers.

Solution: High-throughput screening and automated ranking

The ClonePix 2 Enhanced with Monoclonality Verification can analyze and rank thousands of colonies in a single run using fluorescent detection. This drastically reduces the time spent evaluating clones and helps researchers zero in on the top performers early.

Regulatory Risk from Unverified Monoclonality

Pain Point: Manual methods don’t provide the documented evidence required to prove monoclonality, risking delays in IND filings.

Solution: High-resolution imaging with traceable audit trails

The ClonePix 2 Enhanced with Monoclonality Verification captures high-resolution images of every colony and stores their selection history, providing traceable, auditable proof of monoclonality to meet regulatory expectations.

Inconsistent Clone Quality and Productivity

Pain Point: Morphologically similar clones can vary widely in expression levels, making downstream performance unpredictable.

Solution: Morphology scoring and antibody secretion detection

The ClonePix 2 Enhanced with Monoclonality Verification combines detailed morphological analysis with fluorescent or label-free antibody secretion detection, enabling researchers to select clones that are not only monoclonal but also highly productive.

Labor-Intensive, Error-Prone Workflows

Pain Point: Manual clone picking and tracking are tedious, inconsistent, and unsustainable for scaling.

Solution: End-to-end automation of imaging, scoring, and picking.

With fully automated imaging, scoring, and robotic picking, the ClonePix 2 Enhanced with Monoclonality Verification reduces hands-on time while increasing reproducibility and consistency across high-throughput environments.

 

scientist plating the ClonePix 2

The ClonePix 2 Enhanced for Monoclonality Verification integrates imaging, screening, ranking, and documentation into one platform, giving therapeutic discovery teams everything they need to make smarter decisions faster.

Whether you're preparing for IND submission or scaling up antibody production, the ClonePix 2 Enhanced for Monoclonality Verification enables you to start strong and finish faster.

Cell Line Development Workflow

Enhanced for Monoclonality Verification workflow_20240723

Customer Success Story

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The Fred Hutch Cancer Research Center uses the ClonePix 2 system to efficiently screen and isolate positive hybridoma clones

The Antibody Technology Shared Resource at the Fred Hutch Cancer Research Center offers custom antibody development to academic and industrial research groups. Their unique multiplex screening platform incorporates a ClonePix 2 for identifying and picking monoclonal hybridoma colonies that secrete antibodies to specific proteins, peptides, or small molecule targets. The ClonePix 2 has allowed them to completely redefine their project workflow and capacity.

Molecular Devices: A life science company

We journey alongside researchers, combining next-gen technology and deep expertise to spark bold breakthroughs that push research boundaries and transform lives worldwide.
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We're a trusted life sciences partner to researchers around the world

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*Terms and Conditions Apply. Purchase is subject to Molecular Devices’ standard terms and conditions of sale. Trade in your current ClonePix Mammalian Colony Picker to get an exclusive discount off the list price of a new ClonePix 2 Enhanced with Monoclonality Verification from Molecular Devices. Purchase order must reference promotion code CP25 and must be received by Thursday, July 31, 2025. The trade-in offer cannot be used against any other options and accessories and applies to standard parts only. The offer does not include shipping and handling, installation, or training. The offer cannot be combined with other promotions or discounts. No substitutions or swap-outs are allowed. The offer is not convertible to cash. Offer is not valid for standing orders. All prices exclude local tax which is the responsibility of the customer. Offer void where prohibited. All Molecular Devices products are for research use only. Other restrictions may apply. For our full standard terms and conditions of sale, please visit https://www.moleculardevices.com/terms-and-conditions.