The Axon Advantage: Making Every Ion Count

Gain the advantage in your research with Axon™ – the most cited patch-clamp system, offering unmatched sensitivity, noise reduction and intuitive software to help you publish faster and achieve better results, with fewer hurdles.

41,200+ citations and counting. Add yours with Axon – the gold standard in electrophysiology.

The Axon portfolio provides comprehensive solutions for patch-clamping that includes amplifiers, digitizer, software, and accessories. Our best-in-class instruments facilitate the entire range of patch-clamp technique experiments from the smallest single-channel to the largest macroscopic recordings. With the addition of the user-friendly Axon pCLAMP™ 11 Software Suite for acquisition, recording and analysis, you can push your research a step further and encounter fewer hurdles in your quest for publication. 

Make every ion count with the most sensitive and intuitive instruments in the industry

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Amplification: the most sensitive readings in the industry

Maximise signal to noise ratio, perform multi-channel experiments and measure large currents with the most accurate and sensitive amplifiers on the market.

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Digitization: eliminate noise with 50/60 Hz noise cancellation capabilities

Achieve noise-free data in just one second with a single click. No grounding, no shielding, just the power of the Digidata 1550B Data Acquisition System.

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Analysis: spend less time troubleshooting with software that's (finally) user-friendly

Simplify your acquisition and analysis with pCLAMP 11 Software Suite – and unlock a library of tutorials designed to help you get the most from your data.

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How can Axon give you the advantage in your research?

Our innovative portfolio has been designed to address the pain points of researchers and get you closer to publication. Here's how we can help.

Mastering the patch clamp technique can be challenging, but we’re here to make it easier.

 

Our pCLAMP 11 software is designed with usability at its core, making it the most intuitive data acquisition and analysis platform available.

To support your journey, we offer a rich library of concise tutorials and webinars, and our team of expert electrophysiologists is always ready to assist with any technical questions.

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Noise can compromise the integrity of your data, but our tools are engineered to prevent that.

 

Our HumSilencer™ feature, integrated within the Digidata 1550B, rapidly removes 50/60 Hz interference in just one second upon digitizing your data.

When performing analysis, our dedicated Minis Search tool, included within pCLAMP 11, helps researchers isolate mEPSCs with precision by filtering out background noise.

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With over 41,200 citations, we’re the most trusted name in the industry.

 

From unmatched amplification sensitivity and noise-free digitization to intuitive, robust analysis software, every element is designed to deliver cleaner, more accurate results.

The more precise your data, the clearer your conclusions. The Axon range is purpose-built to reduce variability and enhance signal clarity, so you can spend less time troubleshooting and more time analysing your data.

 

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Explore the most trusted patch-clamp system worldwide

Enter your details to discover how our systems for patch-clamp electrophysiology can help your research go further, faster.

Join thousands of expert researchers that have the Axon Advantage - receiving more sensitive amplification readouts, noise-free data without distortion and streamlined, automated data analysis.

Connect with us to discuss your research needs with one of our electrophysiology specialists and receive more information.

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A complete workflow solution for patch-clamp electrophysiology

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Discover how researchers have gained the advantage with Axon

Neuroscience researchers praise reliability and user-friendliness of amplifier

Wierenga lab uses MultiClamp 700B Microelectrode Amplifier to study the molecular mechanisms of inhibitory synapses

  • Dr. Wierenga’s lab investigates how inhibitory synapses form and function in the brain, using advanced patch-clamp and imaging techniques to understand their role in development, learning, and disorders like autism.
  • AXON’s intuitive pCLAMP11 software and sensitive MultiClamp 700B Microelectrode Amplifier enabled the lab to perform intricate whole-cell recordings with greater ease and reproducibility.
  • The lab performed recordings in developmentally delayed brain slices. The team tracked altered synaptic connectivity and firing properties—critical insights that link electrophysiological changes to behavioural phenotypes in conditions like autism.
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Expert uses pCLAMP protocols to control recording and simulation

University of Texas uses the Axon Patch-Clamp Systems to evaluate signaling mechanisms in the brain underlying memory and recall

  • Dr. Balaji Krishnan’s research focused on understanding how different isoforms of phospholipase D (PLD) influence brain signaling, using an approach that combined electrophysiology, signaling, and behavioral studies. 
  • The team deployed two advanced Axon patch-clamp rigs, which enabled simultaneous dual recordings in both rodent brain slices and cellular models. The integration with pCLAMP 11 Software Suite allowed for precise control of stimulation and recording protocols, offering versatility and signal clarity.
  • The Axon rigs proved instrumental in advancing the lab’s understanding of memory-related signalling pathways. This technological edge is helping the team identify novel intervention points for neurodegenerative diseases like Alzheimer’s, accelerating the path toward effective treatments. 

 


 

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*Price, time to deliver, and specifications will vary based on mutually agreed technical requirements. Solution requirements may cause adjustment to standard performance.