ClonePix 2 Enhanced for Monoclonality Verification

We support researchers across a wide range of applications, backed by decades of expertise in automated colony selection and monoclonality verification.

Cell Line Development
Cell line development is a foundational step in the production of biologics such as monoclonal antibodies. Screening thousands of clones to identify high-producing, stable cell lines is traditionally slow and labor-intensive.
ClonePix automates this process, enabling high-throughput selection of viable, single-cell derived clones—streamlining development and reducing timelines.

Cell Surface Expression Screening
Proteins expressed on the cell surface, like GPCRs, are key therapeutic targets but are notoriously difficult to screen at scale. ClonePix enables high-throughput detection and selection of cells expressing surface proteins using fluorescence-based imaging.
This approach dramatically increases the likelihood of identifying rare, high-expressing clones from large, transfected pools.

Hybridoma Screening
Hybridoma technology remains a gold standard for antibody discovery. Screening fused B-cells for secretion and specificity can be complex and time-consuming. ClonePix, combined with media like CloneMedia and detection reagents like CloneDetect, simplifies the workflow.
From fusion to final clone selection, ClonePix enables rapid isolation of high-producing, antigen-specific hybridomas with full traceability.

Monoclonal Antibody Discovery
Antibody discovery relies on identifying rare, epitope-specific binders. ClonePix automates the screening and picking of monoclonal antibody-producing clones, combining fluorescent antigen labeling with robust imaging.
The result: faster detection, reduced hands-on time, and greater success in isolating therapeutic candidates.

Drug Discovery & Development
Cell-based models are essential in early drug screening, but 2D cultures and manual workflows can limit predictive accuracy. ClonePix helps researchers establish more relevant cell lines faster, supporting screening of functional endpoints and complex phenotypes.
By integrating imaging, screening, and picking into one workflow, ClonePix reduces time-to-data and enhances drug discovery outcomes.