---
title: Work noise-free with HumSilencer™ | Patch-clamp digitizer from Axon
description: Eliminate 50/60 Hz line frequency electrical noise with a single mouse click within one second and get the most accurate data with a digitizer from Molecular Devices.
---

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## SCALE UP ELECTROPHYSIOLOGY

# Manual patch-clamp without 50/60Hz line-frequency noise

![Digitizer and HumSilencer image\_20221201-1](https://info.moleculardevices.com/hs-fs/hubfs/Digitizer%20and%20HumSilencer%20image_20221201-1.png?width=1200&height=1204&name=Digitizer%20and%20HumSilencer%20image_20221201-1.png "Digitizer and HumSilencer image_20221201-1")

## Digitizer that eliminates line-frequency noise with a single mouse click

50 or 60 Hz line frequency electrical noise can either distort or completely drown out the biological signal on the patch-clamp rig. The HumSilencer feature within the Axon™ Digidata® 1550B Data Acquisition System from Molecular Devices provides a quick, adaptive method to remove such noise in one second with a single mouse click without distorting the data.

![MD-Icon-Tick and Arrow-Ease-of-use-Gn](https://info.moleculardevices.com/hs-fs/hubfs/MD-Icon-Tick%20and%20Arrow-Ease-of-use-Gn.png?width=434&height=434&name=MD-Icon-Tick%20and%20Arrow-Ease-of-use-Gn.png)

#### Digitize cellular network studies

With Digidata 1550B system, you can now record cellular networks without noise in a single digitizer while saving money, time, and reducing hassle.

![Noise-cancelling-Gn](https://info.moleculardevices.com/hs-fs/hubfs/Common/Noise-cancelling-Gn.png?width=435&height=434&name=Noise-cancelling-Gn.png)

#### Eliminate line-frequency noise

The HumSilencer™ feature removes 50/60 hz line-frequency noise within one second with a single mouse click.

![Record-Gn](https://info.moleculardevices.com/hs-fs/hubfs/Record-Gn.png?width=61&height=61&name=Record-Gn.png)

#### Record high resolution traces

All eight analog input channels can be simultaneously digitized at an impressive sampling rate of 500 kHz per channel.

[Speak to a specialist](https://info.moleculardevices.com/applications/dd/cns/worknoisefreelp#requestquote)

## Get in touch with our patch-clamp experts

Get in touch with us now to find out how we can help you with your electrophysiological research. Remember to sign up for our mailing list to stay up to date with the latest electrophysiology news, applications, and updates. 

 

### Inquire about the instruments

![Picture1-1](https://info.moleculardevices.com/hubfs/CNS/Picture1-1.png "Picture1-1")

### HumSilencer (HS) enables accurate signal measurement in single-channel recordings

#### Data with HumSilencer enabled in the top panel, raw data in bottom panel

- HS provides a fast adaptive rate (within 1 s) for changing noise patterns
- HS does not distort signal

### Achieve more with pCLAMP 11

#### Fast and effective data analysis turns data into actionable insights and publication-ready results.

- With Clampex 11, longer and more sophisticated  
  protocols can be programmed.
- With ClampFit 11, more precise measurement and faster data analysis are now possible.

[Learn more](https://info.moleculardevices.com/applications/dd/cns/worknoisefreelp#requestquote)

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*\*Price, time to deliver, and specifications will vary based on mutually agreed technical requirements.*

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