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Accelerate your neuroscientific discoveries with Axon Patch-Clamp Intruments
Our comprehensive solutions for patch-clamping facilitate the entire range of patch-clamp technique experiments from the smallest single-channel to the largest macroscopic recordings. The addition of Axon pCLAMP™ 11 Software Suite creates a streamlined workflow, allowing for sophisticated and efficient experiments, and higher quality data generation so you can make a scientific breakthrough even faster.
![Axon workflow_20230214 Axon workflow_20230214](https://info.moleculardevices.com/hs-fs/hubfs/Axon%20workflow_20230214.jpg?width=2968&height=1100&name=Axon%20workflow_20230214.jpg)
![Record-Gn](https://info.moleculardevices.com/hs-fs/hubfs/Record-Gn.png?width=61&height=61&name=Record-Gn.png)
Maximize signal-to-noise ratio
The Axopatch™ 200B Amplifier offers one of the lowest-noise, single-channel recordings available via an innovative actively cooled headstage with capacitor-feedback technology.
![Noise-cancelling-Gn](https://info.moleculardevices.com/hs-fs/hubfs/Common/Noise-cancelling-Gn.png?width=435&height=434&name=Noise-cancelling-Gn.png)
Eliminate line-frequency noise
The HumSilencer™ feature removes 50/60 hz line-frequency noise within one second with a single mouse click.
![Workflow-Gn](https://info.moleculardevices.com/hs-fs/hubfs/Common/Workflow-Gn.png?width=435&height=435&name=Workflow-Gn.png)
Streamline workflows
pCLAMP Software offers a selection of modules and tools that simplifies setup and enables automation of parameters.
Patch-clamp software trusted by researchers worldwide: 41,600+ citations for pCLAMP
![](https://play.vidyard.com/X5bEMAt5nE5rtfa5g7t4hq.jpg)
University of São Paulo uses Axon for patch-clamp recordings in brain slices
pCLAMP 11 acquisition and analysis software
Fast and effective data analysis turns data into actionable insights and publication-ready results.
- With Clampex 11, longer and more sophisticated
protocols can be programmed. - With ClampFit 11, more precise measurement and faster data analysis are now possible.
These researchers used Axon patch-clamp systems to achieve neuroscientific breakthroughs
![nichelle-jackson-detail-1](https://info.moleculardevices.com/hs-fs/hubfs/nichelle-jackson-detail-1.jpg?width=843&height=497&name=nichelle-jackson-detail-1.jpg)
University of Michigan uses Axon patch-clamp systems to investigate NMDAR receptor blockers.
![allegheny-college-lab-photo-1](https://info.moleculardevices.com/hs-fs/hubfs/allegheny-college-lab-photo-1.png?width=900&height=531&name=allegheny-college-lab-photo-1.png)
Allegheny College uses Axon patch-clamp systems to investigate how amyloid beta peptide block ion channels in Alzheimer’s disease.
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University of Texas uses Axon patch-clamp systems to evaluate signaling mechanisms in the brain underlying memory and recall.
Applications
Our solutions can be used across almost the entire range of electrophysiology techniques, from single channel to whole cell to extracellular field-potential recording.
Extracellular recording
• Single-unit recording
• Multi-unit recording
• Field-potential recordings
• Amperometry/voltammetry
![iStock_000010100054Medium (2) iStock_000010100054Medium (2)](https://info.moleculardevices.com/hs-fs/hubfs/iStock_000010100054Medium%20(2).jpg?width=400&height=250&name=iStock_000010100054Medium%20(2).jpg)
Intracellular recording
• Cell-attached/excised patch-clamp
• Whole-cell voltage-clamp
• Whole-cell current-clamp
• Sharp-electrode
![AdobeStock_42939862 AdobeStock_42939862](https://info.moleculardevices.com/hs-fs/hubfs/AdobeStock_42939862.jpeg?width=357&height=250&name=AdobeStock_42939862.jpeg)