Organoid expansion process – efficient, reproducible, scalable
To support your research Molecular Devices can offer a unique, bespoke service for the scale-up of organoid lines using our patent-pending bioprocess, which can produce up to around 6 million organoids per batch using customers' own lines. The PDOs (patient-derived organoids) can then be supplied back to you in their desired quantities and formats, in a customized assay-ready format to meet your individual needs.
Organoid expansion is facilitated by our unique, patented bioprocess and the know-how of our experienced scientists. The semi-automated procedure uses controlled, monitored conditions to produce large numbers of standardized PDOs within a defined size range. Rigorous quality control ensures reduced batch-to-batch and user-to-user variability.
Molecular Devices is leading the way in industrializing the production of standardized, human-derived, healthy and diseased organoids at scale for multiple uses such as drug discovery and organ-on-a-chip applications.
Our patient-derived organoids are:
Multicellular & 3D
PDOs model cell interactions and tissue function.
Scalable and reproducible
Minimal variability both within and between batches facilitates consistency and repeatability in high-throughput applications such as drug screening.
Genetically diverse
PDO model can be selected by tissue or mutation subtype of interest.
Our products and services
Custom Organoid Expansion Service
Bioprocess-grown PDOs at scale with validation and quality assurance
- Expansion of customer’s own or supplied PDO or PDX derived organoid lines
- Bespoke PDO line generation and expansion from PDX tissue (PDXO)
- The bioprocess-grown organoids can be supplied back to you as customized assay-ready vials to be used at your convenience for downstream assays.
*Price, time to deliver, and specifications will vary based on mutually agreed technical requirements. Solution requirements may cause adjustment to standard performance.